RosettaCommons Blog

Source: https://www.destinationhotels.com/suncadia-resort/photo-and-video-gallery We are pleased to announce that Summer RosettaCon will be held at Suncadia Resort in Washington from August 5 - 9, 2024. The conference will start on the late afternoon (4-5 pm) of Monday, and will finish on Friday morning after breakfast with the usual hike / activity day. Pre-RosettaCon will not take place as a separate meeting as the technical talks, discussions and tutorials will be incorporated into the program.  REGISTRATION Registration fees support conference sustainability; this fee is non-refundable and is one mechanism to reduce last minute cancellations and preserve our community resources. Note that the early registration deadline is June 15, 2024. Registrations after this date will incur a higher registration fee.  Please register at www.rosettacon.org . For the first time, all registrations will go through the same interface.  If you need a letter of invitation to apply...

We are pleased to announce registration has opened for our 2024 Rosetta Workshop to be held July 22-24 in person at Vanderbilt University in Nashville, TN. The Vanderbilt Rosetta Workshop is designed to be an introduction to the Rosetta macromolecular modeling suite, focusing on a practical introduction to common Rosetta protocols. Registration for the workshop is on a first-come-first-served basis and is limited to 15 participants. Please register as soon as possible since spots fill quickly.   Participants are responsible for their own travel and accommodation arrangements. We have a block of rooms reserved at a discounted rate, and this information will be shared once registration is completed. For more information, and to register for the workshop, please visit  https://meilerlab.org/rosetta- workshop-summer-2024/ Questions can be directed at Rocco Moretti.

  Dear Rosetta Community, We are thrilled to announce the winners of our recent Science Image Contest! The response we received was great, with an array of breathtaking images showcasing the beauty and complexity of our communities' scientific research. After much deliberation, we have selected the top three submissions that stood out for their creativity and visual impact. Without further ado, let's congratulate our winners: 1st Place: Tom Schlegel - $500 Tom's image captivated us with its stunning detail and artistic composition. Congratulations, Tom, on your well-deserved first-place win! Colorful blender rendering of the lumazine synthase from the hyperthermophile Aquifex aeolicus. 2nd Place: Ian Haydon - $300 Ian's submission impressed us with its striking visuals and unique perspective. His image effortlessly combines artistry with science. Congratulations, Ian, on securing second place! Analogous to perfectly straight, twist-free pieces of lumber, this new class ...

The Winter RosettaCon organizers want to thank Liberum Bio for sponsoring the experimental validation of the designs that they carried out in 8 days starting from digital sequences! Liberum Bio produces proteins at high yields in cell-free systems at a fraction of the usual cost and time via highly engineered strains and state-of-the art reaction mixtures. At Winter RosettaCon 2024 in Boston, the Rosetta Commons in partnership with Liberum Biotech hosted the inaugural Winter Protein Design Games , focusing on the design of Tobacco Etch Virus (TEV) protease variants. TEV protease is commonly used as a tool for sequence-specific protein cleavage, facilitating the purification of proteins without affinity tags. The competition challenged cross-institutional participating teams to engineer TEV proteases that exhibited enhanced substrate cleavage efficiency over the wild-type enzyme.  The competition was straightforward: design TEV protease variants that outperform the wild type in cl...

Dear Rosetta community, Scientists in our community led an effort to develop a framework for the responsible development of AI tools for the life sciences. By establishing a framework of guiding principles, we're at the forefront of promoting safety, security, and ethical responsibility in the development of AI tools. Our commitment deeply embeds biosecurity and ethical considerations into AI advancements, advocating for openness and global cooperation to tackle the pressing challenges of health, energy, and environmental sustainability. This endeavor not only steers AI technology towards responsible growth but also aims to spark breakthroughs that benefit humanity at large. This voluntary commitment has been signed by 154 leading scientists from 28 countries, including Nobel laureate of 2018 Frances Arnold, Microsoft's Chief Scientific Officer Eric Horvitz, the 2018 Turing award winner Yann LeCun, and the Former White House Senior Director for Global Health Security and Biodef...

Dear Rosetta Community and users of Rosetta, We're excited to announce that we have moved the Rosetta code repository to a public repository! We have made this move to honor our longstanding philosophy of sharing our work publicly and making it broadly accessible to scientists. This change marks a new chapter for Rosetta, where future developments will be more collaborative and accessible.  This move required crucial changes to our workflow and licensing terms that are designed to streamline contributions to our platform. The new repository is accessible at https://github.com/RosettaCommons/rosetta . Licensing adjustments: The repository's public status means that non-commercial users no longer need to explicitly sign up for a license to access Rosetta. However, despite being publicly accessible, Rosetta is not open source; redistribution restrictions and other licensing restrictions remain in place for all users. For our commercial users, the existing license will continue as...

Hello friends of Rosetta, We're thrilled to announce an exciting new chapter in our community's journey! After 20 years of wonderful memories at the Sleeping Lady for our annual summer conference, we're moving to a new venue in 2024. As part of our journey of growth and exploration, we are embarking on a new adventure at the Suncadia Resort , outside of Seattle. Our community's evolution is a story of expanding horizons and embracing new possibilities. Suncadia Resort, with its state-of-the-art facilities and size, aligns perfectly with our commitment to growth, accessibility, inclusivity and innovation. This move is a way to test new waters while remaining true to our roots. It's an opportunity to explore new avenues, just as we encourage innovation and new ideas in our field. The Sleeping Lady will always hold a special place in our hearts, and the decision to try Suncadia Resort was made with a spirit of adventure and curiosity.  Join us from Aug 5-9, 2024 at Sun...